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Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes.

Lymphocytes activate adhesion to intracellular adhesion mlecule 1 (ICAM-1) via leukocyte function associated antigen 1 (LFA-1), their major beta 2 integrin, in response to PMA (phorbol 12-myristate 13-acetate) without an increase in the number of receptors expressed. The molecular details of the mec...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Kucik, D F, Dustin, M L, Miller, J M, Brown, E J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507289/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8621804/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118651
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