Cytohesin-1 regulates β-2 integrin-mediated adhesion through both ARF-GEF function and interaction with LFA-1

Intracellular signaling pathways, which regulate the interactions of integrins with their ligands, affect a wide variety of biological functions. Here we provide evidence of how cytohesin-1, an integrin-binding protein and guanine-nucleotide exchange factor (GEF) for ARF GTPases, regulates cell adhe...

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Hauptverfasser: Geiger, Christiane, Nagel, Wolfgang, Boehm, Thomas, van Kooyk, Yvette, Figdor, Carl G., Kremmer, Elisabeth, Hogg, Nancy, Zeitlmann, Lutz, Dierks, Henning, Weber, Kim S.C., Kolanus, Waldemar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC212768/
https://ncbi.nlm.nih.gov/pubmed/10835351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2525
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