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Role of RNA splicing in mediating lineage-specific expression of the von Willebrand factor gene in the endothelium
We previously demonstrated that the first intron of the human von Willebrand factor (vWF) is required for gene expression in the endothelium of transgenic mice. Based on this finding, we hypothesized that RNA splicing plays a role in mediating vWF expression in the vasculature. To address this quest...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663433/ https://ncbi.nlm.nih.gov/pubmed/23529929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-12-473785 |
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