A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model

TCL1 oncogene is overexpressed in aggressive form of human chronic lymphocytic leukemia (CLL) and its dysregulation in mouse B cells causes a CD5-positive leukemia similar to the aggressive form of human CLLs. To identify oncogenes that cooperate with Tcl1, we performed genetic screen in Eμ−TCL1 mic...

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Bibliografiska uppgifter
Huvudupphovsmän: Zanesi, Nicola, Balatti, Veronica, Riordan, Jesse, Burch, Aaron, Rizzotto, Lara, Palamarchuk, Alexey, Cascione, Luciano, Lagana, Alessandro, Dupuy, Adam J., Croce, Carlo M., Pekarsky, Yuri
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Hematology 2013
Ämnen:
Lymphoid Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663428/
https://ncbi.nlm.nih.gov/pubmed/23591791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-486035
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