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NOTCH1 mutations in CLL associated with trisomy 12

Two recent studies reported wholegenome sequencing of chronic lymphocytic leukemia (CLL) samples and found repeated mutations in the XPO1 and NOTCH1 genes. XPO1 was found mutated in 2.4% of cases, while NOTCH1 was found mutated in 12.2% or 15.1% of CLL samples. Here we report the results of sequenci...

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Autori principali: Balatti, Veronica, Bottoni, Arianna, Palamarchuk, Alexey, Alder, Hansjuerg, Rassenti, Laura Z., Kipps, Thomas J., Pekarsky, Yuri, Croce, Carlo M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257004/
https://ncbi.nlm.nih.gov/pubmed/22086416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-386144
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