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NOTCH1 mutations in CLL associated with trisomy 12
Two recent studies reported wholegenome sequencing of chronic lymphocytic leukemia (CLL) samples and found repeated mutations in the XPO1 and NOTCH1 genes. XPO1 was found mutated in 2.4% of cases, while NOTCH1 was found mutated in 12.2% or 15.1% of CLL samples. Here we report the results of sequenci...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3257004/ https://ncbi.nlm.nih.gov/pubmed/22086416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-386144 |
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