Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)

B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia. Deregulation of the T-cell leukemia/lymphoma 1 oncogene (TCL1) in mouse B cells causes a CD5(+) leukemia similar to aggressive human CLL. To examine the mechanisms by which Tcl1 protein exerts its oncogenic activity in B ce...

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Bibliografiset tiedot
Päätekijät: Palamarchuk, Alexey, Yan, Pearlly S., Zanesi, Nicola, Wang, Linan, Rodrigues, Benjamin, Murphy, Mark, Balatti, Veronica, Bottoni, Arianna, Nazaryan, Natalya, Alder, Hansjuerg, Rassenti, Laura, Kipps, Thomas J., Freitas, Michael, Croce, Carlo M., Pekarsky, Yuri
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289317/
https://ncbi.nlm.nih.gov/pubmed/22308499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200003109
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