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Molecular basis of CLL

B-cell chronic lymphocytic leukemia (CLL), the most common leukemia in the Western world, results from an expansion of a rare population of CD5+ mature B-lymphocytes. CLL occurs in two forms, aggressive and indolent. For the most part indolent CLL is characterized by low ZAP-70 expression and mutate...

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Detalhes bibliográficos
Main Authors: Pekarsky, Yuri, Zanesi, Nicola, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997849/
https://ncbi.nlm.nih.gov/pubmed/20863894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2010.09.003
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