NOTCH1 mutations in CLL associated with trisomy 12

Two recent studies reported wholegenome sequencing of chronic lymphocytic leukemia (CLL) samples and found repeated mutations in the XPO1 and NOTCH1 genes. XPO1 was found mutated in 2.4% of cases, while NOTCH1 was found mutated in 12.2% or 15.1% of CLL samples. Here we report the results of sequenci...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Balatti, Veronica, Bottoni, Arianna, Palamarchuk, Alexey, Alder, Hansjuerg, Rassenti, Laura Z., Kipps, Thomas J., Pekarsky, Yuri, Croce, Carlo M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2012
Gaiak:
Plenary Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257004/
https://ncbi.nlm.nih.gov/pubmed/22086416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-10-386144
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