Translocation t(2;11) in CLL cells results in CXCR4/MAML2 fusion oncogene

Recent investigations of chromosomal aberrations in chronic lymphocytic leukemia (CLL) led to a better understanding of the molecular causes of CLL. Here we report a rearrangement between MAML2 (mastermind-like protein 2) and CXCR4 (specific receptor for CXC chemokine stromal cell-derived factor-1)...

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Detalhes bibliográficos
Main Authors: Acunzo, Mario, Romano, Giulia, Wernicke, Dorothee, Balatti, Veronica, Rassenti, Laura Z., dell’Aquila, Marie, Kipps, Thomas J., Pekarsky, Yuri, Croce, Carlo M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093682/
https://ncbi.nlm.nih.gov/pubmed/24855209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-554675
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