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The Structural Basis and Functional Consequences of Interactions Between Tetrodotoxin and Voltage-Gated Sodium Channels

Tetrodotoxin (TTX) is a highly specific blocker of voltage-gated sodium channels. The dissociation constant of block varies with different channel isoforms. Until recently, channel resistance was thought to be primarily imparted by amino acid substitutions at a single position in domain I. Recent wo...

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מידע ביבליוגרפי
Main Authors: Geffeney, Shana L., Ruben, Peter C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Molecular Diversity Preservation International (MDPI) 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663409/
תגים: הוספת תג
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