Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates UV induced melanocyte homeostasis

Keratinocytes contribute to melanocyte activity by influencing their microenvironment, in part, through secretion of paracrine factors. Here we discovered that p53 directly regulates Edn1 expression in epidermal keratinocytes and controls UV-induced melanocyte homeostasis. Selective ablation of EDN1...

Full description

Saved in:
Bibliographic Details
Main Authors: Hyter, Stephen, Coleman, Daniel J., Ganguli-Indra, Gitali, Merrill, Gary F., Ma, Steven, Yanagisawa, Masashi, Indra, Arup K.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663331/
https://ncbi.nlm.nih.gov/pubmed/23279852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12063
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items