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An age-old paradigm challenged: Old baboons generate vigorous humoral immune responses to LcrV, a plague antigen()

Immune senescence in the elderly results in decreased immunity with a concomitant increase in susceptibility to infection and diminished efficacy of vaccination. Nonhuman primate (NHP) models have proven critical for testing of vaccines and therapeutics in the general population, but a model using o...

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Bibliographische Detailangaben
Hauptverfasser: Stacy, Sue, Pasquali, Amanda, Sexton, Valerie L., Cantwell, Angelene M., Kraig, Ellen, Dube, Peter H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663140/
https://ncbi.nlm.nih.gov/pubmed/18566375
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