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An age-old paradigm challenged: Old baboons generate vigorous humoral immune responses to LcrV, a plague antigen()
Immune senescence in the elderly results in decreased immunity with a concomitant increase in susceptibility to infection and diminished efficacy of vaccination. Nonhuman primate (NHP) models have proven critical for testing of vaccines and therapeutics in the general population, but a model using o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3663140/ https://ncbi.nlm.nih.gov/pubmed/18566375 |
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