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Phosphoryl transfer by protein kinase A is captured in a crystal lattice

The catalytic (C) subunit of cAMP-dependent protein kinase (PKA) is a serine/threonine kinase responsible for most of the effects of cAMP signaling, and PKA serves as a prototype for the entire kinase family. Despite multiple studies of PKA, the steps involved in phosphoryl transfer, the roles of th...

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Autors principals: Bastidas, Adam C., Deal, Michael S., Steichen, Jon M., Guo, Yurong, Wu, Jian, Taylor, Susan S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663052/
https://ncbi.nlm.nih.gov/pubmed/23458248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja312237q
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