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Role of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein Kinase
The catalytic (C) subunit of cAMP-dependent protein kinase [protein kinase A (PKA)] is a major target of cAMP signaling, and its regulation is of fundamental importance to biological processes. One mode of regulation is N-myristylation, which has eluded structural and functional characterization so...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597442/ https://ncbi.nlm.nih.gov/pubmed/22617327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.05.021 |
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