Role of N-Terminal Myristylation in the Structure and Regulation of cAMP-Dependent Protein Kinase

The catalytic (C) subunit of cAMP-dependent protein kinase [protein kinase A (PKA)] is a major target of cAMP signaling, and its regulation is of fundamental importance to biological processes. One mode of regulation is N-myristylation, which has eluded structural and functional characterization so...

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Bibliographic Details
Main Authors: Bastidas, Adam C., Deal, Michael S., Steichen, Jon M., Keshwani, Malik M., Guo, Yurong, Taylor, Susan S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597442/
https://ncbi.nlm.nih.gov/pubmed/22617327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.05.021
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