Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase

cAMP-dependent protein kinase A (PKA), ubiquitously expressed in mammalian cells, regulates a plethora of cellular processes through its ability to phosphorylate many protein substrates, including transcription factors, ion channels, apoptotic proteins, transporters, and metabolic enzymes. The PKA c...

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Detalhes bibliográficos
Main Authors: Keshwani, Malik M., Klammt, Christian, von Daake, Sventja, Ma, Yuliang, Kornev, Alexandr P., Choe, Senyon, Insel, Paul A., Taylor, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356610/
https://ncbi.nlm.nih.gov/pubmed/22493239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202741109
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