Functional Recognition of the Modified Human tRNA(Lys3)(UUU) Anticodon Domain by HIV’s Nucleocapsid Protein and a Peptide Mimic

The HIV-1 nucleocapsid protein, NCp7, facilitates the use of human tRNA(Lys3)(UUU) as the primer for reverse transcription. NCp7 also remodels the htRNA’s amino acid accepting stem and anticodon domains in preparation for their being annealed to the viral genome. To understand the possible influence...

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Autors principals: Graham, William D., Barley-Maloney, Lise, Stark, Caren J., Kaur, Amarpreet, Stolyarchuk, Khrystyna, Sproat, Brian, Leszczynska, Grazyna, Malkiewicz, Andrzej, Safwat, Nedal, Mucha, Piotr, Guenther, Richard, Agris, Paul F.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662833/
https://ncbi.nlm.nih.gov/pubmed/21762809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.04.025
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