Unconventional structure of tRNA(Lys)SUU anticodon explains tRNA's role in bacterial and mammalian ribosomal frameshifting and primer selection by HIV-1.

Transfer RNA(Lys)SUU, with a 5-modified-2-thiouridine at wobble position 34, facilitates -1 frameshifts for correct translation of the Escherichia coli DNA polymerase gamma subunit and retroviral polymerases. Peptidyl-tRNA(Lys)SUU prematurely terminates translation more often than other tRNAs. In or...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Agris, P F, Guenther, R, Ingram, P C, Basti, M M, Stuart, J W, Sochacka, E, Malkiewicz, A
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369493/
https://ncbi.nlm.nih.gov/pubmed/9085848
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