Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

Neuromyelitis optica (NMO) is an autoimmune disease targeting aquaporin 4 (AQP4), localized mainly at the astrocytic foot processes. Loss of AQP4 and glial fibrillary acidic protein (GFAP) was reported, but the pathological significance of astrocytopathy is still controversial. Here we show that act...

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Bibliografiske detaljer
Main Authors: Misu, Tatsuro, Höftberger, Romana, Fujihara, Kazuo, Wimmer, Isabella, Takai, Yoshiki, Nishiyama, Shuhei, Nakashima, Ichiro, Konno, Hidehiko, Bradl, Monika, Garzuly, Ferenc, Itoyama, Yasuto, Aoki, Masashi, Lassmann, Hans
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2013
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661909/
https://ncbi.nlm.nih.gov/pubmed/23579868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1116-7
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