Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

Neuromyelitis optica (NMO) is an autoimmune disease targeting aquaporin 4 (AQP4), localized mainly at the astrocytic foot processes. Loss of AQP4 and glial fibrillary acidic protein (GFAP) was reported, but the pathological significance of astrocytopathy is still controversial. Here we show that act...

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Autors principals: Misu, Tatsuro, Höftberger, Romana, Fujihara, Kazuo, Wimmer, Isabella, Takai, Yoshiki, Nishiyama, Shuhei, Nakashima, Ichiro, Konno, Hidehiko, Bradl, Monika, Garzuly, Ferenc, Itoyama, Yasuto, Aoki, Masashi, Lassmann, Hans
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2013
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661909/
https://ncbi.nlm.nih.gov/pubmed/23579868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1116-7
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