Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat

It is well established that the binding of pathogenic aquaporin-4 (AQP4)-specific autoantibodies to astrocytes may initiate a cascade of events culminating in the destruction of these cells and in the formation of large tissue-destructive lesions typical for patients with neuromyelitis optica spectr...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol
Autori principali: Hillebrand, Sophie, Schanda, Kathrin, Nigritinou, Magdalini, Tsymala, Irina, Böhm, Denise, Peschl, Patrick, Takai, Yoshiki, Fujihara, Kazuo, Nakashima, Ichiro, Misu, Tatsuro, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2018
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514074/
https://ncbi.nlm.nih.gov/pubmed/30564980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1950-8
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