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Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat
It is well established that the binding of pathogenic aquaporin-4 (AQP4)-specific autoantibodies to astrocytes may initiate a cascade of events culminating in the destruction of these cells and in the formation of large tissue-destructive lesions typical for patients with neuromyelitis optica spectr...
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| Publicado no: | Acta Neuropathol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6514074/ https://ncbi.nlm.nih.gov/pubmed/30564980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1950-8 |
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