Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats

BACKGROUND: Neuromyelitis optica (NMO) is a severe, disabling disease of the central nervous system (CNS) characterized by the formation of astrocyte-destructive, neutrophil-dominated inflammatory lesions in the spinal cord and optic nerves. These lesions are initiated by the binding of pathogenic a...

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Detalhes bibliográficos
Main Authors: Kitic, Maja, Hochmeister, Sonja, Wimmer, Isabella, Bauer, Jan, Misu, Tatsuro, Mader, Simone, Reindl, Markus, Fujihara, Kazuo, Lassmann, Hans, Bradl, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776214/
https://ncbi.nlm.nih.gov/pubmed/24252536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-5
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