Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

Neuromyelitis optica (NMO) is an autoimmune disease targeting aquaporin 4 (AQP4), localized mainly at the astrocytic foot processes. Loss of AQP4 and glial fibrillary acidic protein (GFAP) was reported, but the pathological significance of astrocytopathy is still controversial. Here we show that act...

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Detalhes bibliográficos
Main Authors: Misu, Tatsuro, Höftberger, Romana, Fujihara, Kazuo, Wimmer, Isabella, Takai, Yoshiki, Nishiyama, Shuhei, Nakashima, Ichiro, Konno, Hidehiko, Bradl, Monika, Garzuly, Ferenc, Itoyama, Yasuto, Aoki, Masashi, Lassmann, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661909/
https://ncbi.nlm.nih.gov/pubmed/23579868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1116-7
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