Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

Neuromyelitis optica (NMO) is an autoimmune disease targeting aquaporin 4 (AQP4), localized mainly at the astrocytic foot processes. Loss of AQP4 and glial fibrillary acidic protein (GFAP) was reported, but the pathological significance of astrocytopathy is still controversial. Here we show that act...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Misu, Tatsuro, Höftberger, Romana, Fujihara, Kazuo, Wimmer, Isabella, Takai, Yoshiki, Nishiyama, Shuhei, Nakashima, Ichiro, Konno, Hidehiko, Bradl, Monika, Garzuly, Ferenc, Itoyama, Yasuto, Aoki, Masashi, Lassmann, Hans
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2013
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661909/
https://ncbi.nlm.nih.gov/pubmed/23579868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1116-7
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki