Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction

Insulin resistance is characterized by excessive endothelial cell generation of potentially cytotoxic concentrations of reactive oxygen species. We examined the role of NADPH oxidase (Nox) and specifically Nox2 isoform in superoxide generation in two complementary in vivo models of human insulin res...

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Bibliografische gegevens
Hoofdauteurs: Sukumar, Piruthivi, Viswambharan, Hema, Imrie, Helen, Cubbon, Richard M., Yuldasheva, Nadira, Gage, Matthew, Galloway, Stacey, Skromna, Anna, Kandavelu, Parkavi, Santos, Celio X., Gatenby, V. Kate, Smith, Jessica, Beech, David J., Wheatcroft, Stephen B., Channon, Keith M., Shah, Ajay M., Kearney, Mark T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2013
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661635/
https://ncbi.nlm.nih.gov/pubmed/23349484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1294
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