Nox2 NADPH Oxidase Has a Critical Role in Insulin Resistance–Related Endothelial Cell Dysfunction

Insulin resistance is characterized by excessive endothelial cell generation of potentially cytotoxic concentrations of reactive oxygen species. We examined the role of NADPH oxidase (Nox) and specifically Nox2 isoform in superoxide generation in two complementary in vivo models of human insulin res...

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Autors principals: Sukumar, Piruthivi, Viswambharan, Hema, Imrie, Helen, Cubbon, Richard M., Yuldasheva, Nadira, Gage, Matthew, Galloway, Stacey, Skromna, Anna, Kandavelu, Parkavi, Santos, Celio X., Gatenby, V. Kate, Smith, Jessica, Beech, David J., Wheatcroft, Stephen B., Channon, Keith M., Shah, Ajay M., Kearney, Mark T.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661635/
https://ncbi.nlm.nih.gov/pubmed/23349484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1294
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