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Impact of Glucocorticoid Receptor Density on Ligand-Independent Dimerization, Cooperative Ligand-Binding and Basal Priming of Transactivation: A Cell Culture Model

Glucocorticoid receptor (GR) levels vary between tissues and individuals and are altered by physiological and pharmacological effectors. However, the effects and implications of differences in GR concentration have not been fully elucidated. Using three statistically different GR concentrations in t...

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Detalhes bibliográficos
Main Authors: Robertson, Steven, Rohwer, Johann M., Hapgood, Janet P., Louw, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661511/
https://ncbi.nlm.nih.gov/pubmed/23717665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064831
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