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The Ligand Binding Domain Controls Glucocorticoid Receptor Dynamics Independent of Ligand Release

Ligand binding to the glucocorticoid receptor (GR) results in receptor binding to glucocorticoid response elements (GREs) and the formation of transcriptional regulatory complexes. Equally important, these complexes are continuously disassembled, with active processes driving GR off GREs. We found t...

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Autors principals: Meijsing, Sebastiaan H., Elbi, Cem, Luecke, Hans F., Hager, Gordon L., Yamamoto, Keith R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899895/
https://ncbi.nlm.nih.gov/pubmed/17261597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01570-06
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