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The Ligand Binding Domain Controls Glucocorticoid Receptor Dynamics Independent of Ligand Release

Ligand binding to the glucocorticoid receptor (GR) results in receptor binding to glucocorticoid response elements (GREs) and the formation of transcriptional regulatory complexes. Equally important, these complexes are continuously disassembled, with active processes driving GR off GREs. We found t...

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Détails bibliographiques
Auteurs principaux: Meijsing, Sebastiaan H., Elbi, Cem, Luecke, Hans F., Hager, Gordon L., Yamamoto, Keith R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899895/
https://ncbi.nlm.nih.gov/pubmed/17261597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01570-06
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