Regulation of V(H) Replacement by B Cell Receptor (BCR)-mediated Signaling in Human Immature B Cells

V(H) replacement provides a unique RAG-mediated recombination mechanism to edit non-functional IgH genes or IgH genes encoding self reactive B cell receptors (BCRs) and contributes to the diversification of antibody repertoire in mouse and human. Currently, it is not clear how V(H) replacement is re...

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Hauptverfasser: Liu, Jing, Lange, Miles D., Hong, Sang Yong, Xie, Wanqin, Xu, Kerui, Huang, Lin, Yu, Yangsheng, Ehrhardt, Götz R. A., Zemlin, Michael, Burrows, Peter D., Su, Kaihong, Carter, Robert H., Zhang, Zhixin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660396/
https://ncbi.nlm.nih.gov/pubmed/23630348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102503
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