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Accumulation of V(H) Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human
V(H) replacement refers to RAG-mediated secondary recombination of the IgH genes, which renews almost the entire V(H) gene coding region but retains a short stretch of nucleotides as a V(H) replacement footprint at the newly generated V(H)–D(H) junction. To explore the biological significance of V(H...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4105631/ https://ncbi.nlm.nih.gov/pubmed/25101087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00345 |
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