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Contribution of V(H) Replacement Products in Mouse Antibody Repertoire

V(H) replacement occurs through RAG-mediated recombination between the cryptic recombination signal sequence (cRSS) near the 3′ end of a rearranged V(H) gene and the 23-bp RSS from an upstream unrearranged V(H) gene. Due to the location of the cRSS, V(H) replacement leaves a short stretch of nucleot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Lin, Lange, Miles D., Yu, Yangsheng, Li, Song, Su, Kaihong, Zhang, Zhixin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585286/
https://ncbi.nlm.nih.gov/pubmed/23469094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057877
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