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Concomitant TAR-DNA-Binding Protein 43 Pathology Is Present in Alzheimer Disease and Corticobasal Degeneration but Not in Other Tauopathies

Pathologic TAR-DNA-binding protein 43 (TDP-43) is a disease protein in frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis. We studied the presence, frequency, and distribution of TDP-43 pathology by immunohistochemistry and biochemistry in...

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Detalhes bibliográficos
Main Authors: Uryu, Kunihiro, Nakashima-Yasuda, Hanae, Forman, Mark S., Kwong, Linda K., Clark, Christopher M., Grossman, Murray, Miller, Bruce L., Kretzschmar, Hans A., Lee, Virginia M.-Y., Trojanowski, John Q., Neumann, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659339/
https://ncbi.nlm.nih.gov/pubmed/18520774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e31817713b5
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