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TAR DNA-binding protein 43 in neurodegenerative disease
In 2006, TAR DNA-binding protein 43 (TDP-43), a highly conserved nuclear protein, was identified as the major disease protein in amyotrophic lateral sclerosis (ALS) and in the most common variant of frontotemporal lobar degeneration (FTLD), FTLD-U, which is characterized by cytoplasmic inclusions th...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892118/ https://ncbi.nlm.nih.gov/pubmed/20234357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2010.18 |
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