Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
Several mouse models have already proved valuable for investigating hypertrophic responses to cardiac stress. Here, we characterize one caused by a well defined single copy transgene, RenTgMK, that genetically clamps plasma renin and thence angiotensin II at high levels. All of the transgenic males...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365751/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307333101 |
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