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Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
Several mouse models have already proved valuable for investigating hypertrophic responses to cardiac stress. Here, we characterize one caused by a well defined single copy transgene, RenTgMK, that genetically clamps plasma renin and thence angiotensin II at high levels. All of the transgenic males...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2004
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365751/ https://ncbi.nlm.nih.gov/pubmed/14978280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307333101 |
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