Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.

The renin-angiotensin system (RAS) is the most important regulatory system of electrolyte homeostasis and blood pressure. We report here the development of transgenic rats carrying the human angiotensinogen TGR-(hAOGEN) and human renin TGR(hREN) genes. The plasma levels and tissue distribution of th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ganten, D, Wagner, J, Zeh, K, Bader, M, Michel, J B, Paul, M, Zimmermann, F, Ruf, P, Hilgenfeldt, U, Ganten, U
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7806
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