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Role for neuronal insulin resistance in neurodegenerative diseases

Impairment of insulin signaling in the brain has been linked to neurodegenerative diseases. To test the hypothesis that neuronal insulin resistance contributes to defects in neuronal function, we have performed a detailed analysis of brain/neuron-specific insulin receptor knockout (NIRKO) mice. We f...

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書誌詳細
主要な著者: Schubert, Markus, Gautam, Dinesh, Surjo, David, Ueki, Kojihiko, Baudler, Stephanie, Schubert, Dominic, Kondo, Tatsuya, Alber, Jens, Galldiks, Norbert, Küstermann, Eckehardt, Arndt, Saskia, Jacobs, Andreas H., Krone, Wilhelm, Kahn, C. Ronald, Brüning, Jens C.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC365750/
https://ncbi.nlm.nih.gov/pubmed/14981233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308724101
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