The SPANX gene family of cancer/testis-specific antigens: Rapid evolution and amplification in African great apes and hominids

Human sperm protein associated with the nucleus on the X chromosome (SPANX) genes comprise a gene family with five known members (SPANX-A1, -A2, -B, -C, and -D), encoding cancer/testis-specific antigens that are potential targets for cancer immunotherapy. These highly similar paralogous genes cluste...

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Autors principals: Kouprina, Natalay, Mullokandov, Michael, Rogozin, Igor B., Collins, N. Keith, Solomon, Greg, Otstot, John, Risinger, John I., Koonin, Eugene V., Barrett, J. Carl, Larionov, Vladimir
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC365747/
https://ncbi.nlm.nih.gov/pubmed/14973187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308532100
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