Chargement en cours...
Structure of the human smoothened receptor 7TM bound to an antitumor agent
The smoothened (SMO) receptor, a key signal transducer in the Hedgehog (Hh) signaling pathway is both responsible for the maintenance of normal embryonic development and implicated in carcinogenesis. The SMO receptor is classified as a class Frizzled (class F) G protein-coupled receptor (GPCR), alth...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3657389/ https://ncbi.nlm.nih.gov/pubmed/23636324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12167 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|