Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

Atraumatic application of attenuated SIVmac239Δnef vaccine to the tonsils of rhesus macaques provided protection against challenge 26 weeks later with infectious SIVmac251 applied through this route. Early events at the mucosal portal of entry of challenge virus were followed. Wild-type virus was de...

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Bibliographic Details
Main Authors: Tenner-Racz, Klara, Hennig, Christiane Stahl, Überla, Klaus, Stoiber, Heribert, Ignatius, Ralf, Heeney, Jonathan, Steinman, Ralph M., Racz, Paul
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC365737/
https://ncbi.nlm.nih.gov/pubmed/14970317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308677101
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