Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors

BACKGROUND: We investigated the interplay between complement and antibodies upon priming with single-cycle replicating viral vectors (SCIV) encoding SIV antigens combined with Adeno5-SIV or SCIV pseudotyped with murine leukemia virus envelope boosting strategies. The vaccine was applied via spray-im...

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Dettagli Bibliografici
Autori principali: Falkensammer, Barbara, Rubner, Barbara, Hiltgartner, Alexander, Wilflingseder, Doris, Hennig, Christiane Stahl, Kuate, Seraphin, Überla, Klaus, Norley, Stephen, Strasak, Alexander, Racz, Paul, Stoiber, Heribert
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713197/
https://ncbi.nlm.nih.gov/pubmed/19545395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-60
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