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Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

Atraumatic application of attenuated SIVmac239Δnef vaccine to the tonsils of rhesus macaques provided protection against challenge 26 weeks later with infectious SIVmac251 applied through this route. Early events at the mucosal portal of entry of challenge virus were followed. Wild-type virus was de...

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Detalhes bibliográficos
Main Authors: Tenner-Racz, Klara, Hennig, Christiane Stahl, Überla, Klaus, Stoiber, Heribert, Ignatius, Ralf, Heeney, Jonathan, Steinman, Ralph M., Racz, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365737/
https://ncbi.nlm.nih.gov/pubmed/14970317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308677101
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