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Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering
Bim, a proapoptotic BH3-only member of the Bcl-2 protein family, is required for central and peripheral deletion of T lymphocytes. Mechanisms regulating Bim activity in T cells remain poorly understood. We show that expression of Bim is up-regulated in human T cells after polyclonal or specific T ce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365736/ https://ncbi.nlm.nih.gov/pubmed/14970329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400005101 |
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