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An antibacterial from Hypericum acmosepalum inhibits ATP-dependent MurE ligase from Mycobacterium tuberculosis

In a project to characterise new antibacterial chemotypes from plants, hyperenone A and hypercalin B were isolated from the hexane and chloroform extracts of the aerial parts of Hypericum acmosepalum. The structures of both compounds were characterised by extensive one- and two-dimensional nuclear m...

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Detalhes bibliográficos
Main Authors: Osman, Khadijo, Evangelopoulos, Dimitrios, Basavannacharya, Chandrakala, Gupta, Antima, McHugh, Timothy D., Bhakta, Sanjib, Gibbons, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657136/
https://ncbi.nlm.nih.gov/pubmed/22079533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijantimicag.2011.09.018
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