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Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus
[Image: see text] MurD and MurE ligases, consecutive enzymes participating in the intracellular steps of bacterial peptidoglycan biosynthesis, are important targets for antibacterial drug discovery. We have designed, synthesized, and evaluated the first d-glutamic acid-containing dual inhibitor of M...
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| Główni autorzy: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American
Chemical Society
2012
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| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4025807/ https://ncbi.nlm.nih.gov/pubmed/24900523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300047h |
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