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Structural basis of p38α regulation by hematopoietic tyrosine phosphatase

MAP kinases regulate essential cellular events, including cell growth, differentiation and inflammation. The solution structure of a complete MAPK–MAPK-regulatory protein complex, p38α–HePTP, was determined, enabling a comprehensive investigation of the molecular basis of specificity and fidelity in...

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Detalhes bibliográficos
Main Authors: Francis, Dana M, Różycki, Bartosz, Koveal, Dorothy, Hummer, Gerhard, Page, Rebecca, Peti, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657131/
https://ncbi.nlm.nih.gov/pubmed/22057126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.707
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