Docking Interactions of Hematopoietic Tyrosine Phosphatase (HePTP) with the MAP Kinases ERK2 and p38α

Hematopoietic tyrosine phosphatase (HePTP) regulates orthogonal MAP kinase signaling cascades by dephosphorylating both ERK and p38. HePTP recognizes a docking site (D-recruitment site, DRS) on its targets using a conserved N-terminal sequence motif (D-motif). Using solution NMR spectroscopy and iso...

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Main Authors: Piserchio, Andrea, Francis, Dana M, Koveal, Dorothy, Dalby, Kevin N., Page, Rebecca, Peti, Wolfgang, Ghose, Ranajeet
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548032/
https://ncbi.nlm.nih.gov/pubmed/23030599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3012725
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