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Crystal structure of the complex between thrombin and the central “E” region of fibrin
Nonsubstrate interactions of thrombin with fibrin play an important role in modulating its procoagulant activity. To establish the structural basis for these interactions, we crystallized d-Phe-Pro-Arg-chloromethyl ketone-inhibited human thrombin in complex with a fragment, E(ht), corresponding to t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365687/ https://ncbi.nlm.nih.gov/pubmed/14978285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0303440101 |
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