Φορτώνει......
Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene.
Compared with normal erbB-2 gp185, mutant erbB-2 proteins generated by mutations either in the transmembrane domain or by NH2-terminal deletion are able to transform NIH 3T3 cells at a 10- to 100-fold greater efficiency. Mutant proteins of both classes show increased tyrosine kinase activity, sugges...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
1988
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365664/ https://ncbi.nlm.nih.gov/pubmed/2907606 |
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