Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene.

Compared with normal erbB-2 gp185, mutant erbB-2 proteins generated by mutations either in the transmembrane domain or by NH2-terminal deletion are able to transform NIH 3T3 cells at a 10- to 100-fold greater efficiency. Mutant proteins of both classes show increased tyrosine kinase activity, sugges...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Segatto, O, King, C R, Pierce, J H, Di Fiore, P P, Aaronson, S A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 1988
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365664/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2907606/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5570
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller