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Prognostic impact and targeting of CRM1 in acute myeloid leukemia
Chromosomal region maintenance 1 (CRM1) is a nuclear export receptor recognizing proteins bearing a leucine-rich nuclear export signal. CRM1 is involved in nuclear export of tumor suppressors such as p53. We investigated the prognostic significance of CRM1 in acute myeloid leukemia (AML) and effects...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society of Hematology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656451/ https://ncbi.nlm.nih.gov/pubmed/23564911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-08-447581 |
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